Blockquote[quote=“utahbiker, post:13, topic:3297”]
This thread doesn’t seem encouraging with the athletic DNA results. I’m curious if there have been anyone at all that’s had a positive experience from doing athletic DNA tests. Something that helped provide them insight into their training or nutrition that had positive and noticeable differences.
I had positive experiences but I didn’t use a cookie cutter genetic test. I did my own deep dive. With the caffeine metabolism information I changed my behavior in caffeine consumption and avoid it in the afternoons as the half life of caffeine is 5-6 hours and mine is likely longer. As sleep is the major component of recovery, I am looking to improve my sleep quality as much as possible. I have felt fresher for my workouts as I tend to not get enough sleep. When the time comes, I will be looking forward to follow a protocol of weaning myself off daily caffeine consumption to maximize my race day caffeine effectiveness. Due to my genotype, I know I have to give my body a little more time to do this form of periodization.
With the other genotype information I am paying close attention to, I know to check my homocysteine levels to make sure there isn’t a deficiency. Vitamin D is another factor to look for when I run my labs. With proper diet and supplementation, this has not been a problem.
Combined with familial and genetic risks I’ve found, I should be concerned with my increased likelihood of developing type 2 diabetes. I am more careful with my diet and although I am young and healthy, I pay attention to the glycemic load of my meals by glucose testing and am making sure I am earning my carbs as coach Chad always says. Glycemic load is personalized and a potato or banana may have very different effects between individuals.
I am an APOE3/APOE4 genotype which gives me a lifetime probability of Alzheimer’s of about 30%. Current science is showing a link between diet, diabetes and Alzheimer’s risk. It is possible that a lower carb diet is more suitable for long term health and I take the base building phase of training seriously to make sure my fat metabolism is more efficient.
I didn’t need a genetic test to know I am ALDH2 deficient, but I am. I like beer/whisky but my ability to break down the acetaldehyde byproduct is diminished because of the mutation. I can’t consume as much alcohol as others without training repercussions because of the mutation. I didn’t need the genetic test because I already knew from experience but It’s just cool to just know. Also, risk of mouth, throat, esophageal, stomach cancer is increased as evidenced in epidemiological studies. Mechanistically it’s probably the acetaldehyde increasing the risk as it’s a carcinogen. Just something to keep in the back of my mind when troubleshooting my health sometime down the line. I’m not the hypochondriac type but I am mindful that I shouldn’t ignore signs and symptoms too. I like to know the odds.
Soooo yea, that’s just off the top of my head but there is a lot to be gained from the test. The data is there, but it’s ultimately up to how you use it. Unless you have some sort of nutritional deficiency, it’s unlikely you’ll see immediate results. I find that it may be a powerful tool to provide objective data to modify your behavior to optimize your training regimen.