Ibuprofen’s effect on male endocrine system

Nutrition
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“A randomized, placebo-controlled trial finds 600 mg of ibuprofen per day for 1.5 months induced hypogonadism in men as measured by a 23% decrease in free testosterone/LH ratio”

Yikes.

https://www.pnas.org/content/115/4/E715

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The analgesics acetaminophen/paracetamol and ibuprofen have previously been shown to inhibit the postexercise response in muscles by repressing transcription (38⇓–40).

Eek. Also, I couldn’t find in the study whether testosterone levels returned to normal when they stopped taking ibruprofen…

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